:root{--ink:#142b32;--muted:#52666b;--teal:#156b69;--mint:#d9eeea;--paper:#fafaf6;--line:#d7e0dc;--accent:#ed8f63;--white:#fff;--hero-a:#e4f1ed;--hero-b:#f5f5ec;--hero-c:#f7e7d9;--footer:#10272c;--art-1:#7bc0ae;--art-2:#b9ded3;--art-3:#e6f2ed;--orbit:#94bdb3}.theme-clinical{--ink:#102c46;--muted:#4d657a;--teal:#1667a8;--mint:#dbeaf6;--paper:#f7fafd;--line:#d4e0ea;--accent:#dc684c;--hero-a:#e3f0fa;--hero-b:#f5f9fc;--hero-c:#edf4fa;--footer:#0b2942;--art-1:#67a9d7;--art-2:#b7d9ed;--art-3:#e4f1f8;--orbit:#7fb0cf}.theme-research{--ink:#36293b;--muted:#6b596e;--teal:#7b4168;--mint:#eee0e9;--paper:#fcf9f6;--line:#e4d8dc;--accent:#db7655;--hero-a:#f2e8ee;--hero-b:#faf5ef;--hero-c:#f6e3d5;--footer:#302334;--art-1:#c487aa;--art-2:#e2bfd1;--art-3:#f2e5eb;--orbit:#bc8da7}
*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--paper);color:var(--ink);font-family:Segoe UI,Arial,sans-serif;line-height:1.6}a{color:var(--teal)}button,input,select,textarea{font:inherit}button{cursor:pointer}.container{width:min(1160px,calc(100% - 48px));margin:auto}.narrow{max-width:790px}.skip{position:absolute;left:-9999px;top:0;background:#fff;padding:10px}.skip:focus{left:10px;z-index:20}.site-header{background:#fff;border-bottom:1px solid var(--line);position:relative;z-index:10}.nav-wrap{display:flex;align-items:center;justify-content:space-between;gap:32px;min-height:84px}.brand{text-decoration:none;color:var(--ink);font-weight:800;letter-spacing:-.06em;font-size:27px;line-height:1}.brand span{color:var(--accent)}.brand small{display:block;font-size:9px;letter-spacing:.16em;font-weight:700;margin-top:8px}.site-header nav{display:flex;align-items:center;gap:22px;flex-wrap:wrap}.site-header nav a{text-decoration:none;color:var(--ink);font-size:14px;font-weight:600}.site-header nav a:hover,.text-link:hover{text-decoration:underline}.site-header .nav-portal{color:var(--teal)}.site-header .lang{border-left:1px solid var(--line);padding-left:18px}.theme-picker{display:inline-flex;align-items:center;gap:7px;padding-left:3px}.site-header nav .theme-dot{display:block;width:16px;height:16px;border-radius:50%;border:2px solid #fff;box-shadow:0 0 0 1px #9babae}.site-header nav .theme-dot:hover{transform:scale(1.12);text-decoration:none}.theme-dot.sage{background:#227b75}.theme-dot.clinical{background:#2976b5}.theme-dot.research{background:#925477}.theme-dot[aria-current=true]{box-shadow:0 0 0 2px var(--ink)}.hero{background:linear-gradient(120deg,var(--hero-a) 0%,var(--hero-b) 62%,var(--hero-c) 100%);overflow:hidden}.hero-grid{min-height:600px;display:grid;grid-template-columns:1.05fr .95fr;align-items:center;gap:30px;padding-top:60px;padding-bottom:70px}.eyebrow,.section-label{font-weight:800;letter-spacing:.16em;font-size:11px;color:var(--teal)}h1,h2,h3{line-height:1.12;letter-spacing:-.035em}h1{font-size:clamp(42px,5vw,68px);max-width:760px;margin:20px 0 23px}h2{font-size:clamp(30px,3vw,44px)}h3{font-size:23px}.lead{font-size:21px;line-height:1.55;color:var(--muted);max-width:650px}.medical-tags{display:flex;gap:8px;flex-wrap:wrap;margin-top:24px}.medical-tags span{border:1px solid color-mix(in srgb,var(--teal) 35%,transparent);background:color-mix(in srgb,var(--mint) 60%,white);color:var(--teal);border-radius:40px;padding:5px 11px;font-size:12px;font-weight:800;letter-spacing:.03em}.actions{display:flex;gap:26px;align-items:center;margin-top:28px;flex-wrap:wrap}.button{display:inline-flex;align-items:center;justify-content:center;background:var(--teal);color:#fff;text-decoration:none;border:0;border-radius:3px;padding:13px 22px;font-weight:700}.button:hover{filter:brightness(.88)}.button.secondary{background:#e8eeeb;color:var(--ink)}.text-link{font-weight:700;text-decoration:none}.hero-art{height:430px;position:relative;border-radius:50%;background:radial-gradient(circle at 52% 50%,#f9fbf7 0 9%,var(--art-1) 10% 11%,transparent 12%),radial-gradient(circle at 50% 50%,var(--art-2) 0 30%,transparent 31%),radial-gradient(circle at 50% 50%,var(--art-3) 0 55%,transparent 56%);box-shadow:inset 0 0 0 1px var(--line)}.orbit{border:1px solid var(--orbit);border-radius:50%;position:absolute;inset:35px;transform:rotate(-20deg) scaleY(.55)}.orbit-b{inset:0;transform:rotate(48deg) scaleY(.57)}.pulse{position:absolute;width:13px;height:13px;background:var(--accent);border-radius:50%;left:16%;top:37%;box-shadow:0 0 0 9px color-mix(in srgb,var(--accent) 25%,transparent)}.art-label{position:absolute;right:16%;bottom:16%;font-weight:800;font-size:34px;letter-spacing:-.08em;color:var(--teal)}.art-label span{color:var(--accent)}.section-spaced,.intro-section{padding-top:90px;padding-bottom:100px}.intro-grid{display:grid;grid-template-columns:1fr 1fr;gap:65px}.intro-grid h2{margin:12px 0}.intro-grid p{font-size:18px;color:var(--muted);margin-top:16px}.band{background:var(--ink);color:#fff;padding:42px 0}.stat-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:35px}.stat-grid div{border-right:1px solid #587076}.stat-grid div:last-child{border:0}.stat-grid strong{font-size:46px;line-height:1;display:block}.stat-grid span{color:#c3d4d2}.card-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:18px;margin-top:35px}.card{background:#fff;border:1px solid var(--line);padding:32px;min-height:250px}.card span{color:var(--teal);font-weight:800;font-size:12px}.card h3{margin:30px 0 10px}.card p{color:var(--muted)}.page-hero{background:var(--hero-a);padding:75px 0 80px}.page-hero h1{margin-bottom:0}.page-hero .lead{margin-top:20px}.prose p,.prose li{font-size:18px;color:var(--muted)}.prose h2{margin:50px 0 15px}.prose h2:first-child{margin-top:0}.work-list{padding-left:24px}.work-list li{padding:9px 0;border-bottom:1px solid var(--line)}.small-note{font-size:14px!important;margin-top:45px}.people-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:1px;background:var(--line);border:1px solid var(--line)}.person{background:#fff;padding:30px}.person span{font-size:12px;font-weight:800;color:var(--teal)}.person h2{font-size:28px;margin:15px 0 8px}.person p{color:var(--muted);margin:0}.post{padding:30px 0;border-bottom:1px solid var(--line)}.post time{font-size:13px;color:var(--teal);font-weight:700}.post h3{margin:8px 0}.post p{white-space:pre-line;color:var(--muted)}.empty{color:var(--muted);padding:35px 0}.footer{background:var(--footer);color:#fff;padding:50px 0}.footer-grid{display:grid;grid-template-columns:minmax(0,1.6fr) minmax(180px,.9fr) minmax(280px,1.25fr);gap:52px;align-items:start}.footer p{color:#b8ccca;font-size:14px}.footer-funding img{display:block;width:min(100%,300px);height:auto;margin-top:20px}.notice{background:var(--mint);padding:12px 20px;margin-top:20px;border-left:4px solid var(--teal)}.portal-wrap{padding:55px 0 100px}.portal-head{display:flex;justify-content:space-between;align-items:end;gap:25px;margin-bottom:35px}.portal-head h1{font-size:42px;margin:8px 0}.portal-nav{display:flex;gap:8px;flex-wrap:wrap;margin-bottom:35px;border-bottom:1px solid var(--line);padding-bottom:14px}.portal-nav a{display:inline-block;text-decoration:none;padding:7px 13px;color:var(--ink);font-weight:600}.portal-nav a:hover{background:var(--mint)}.panel{background:#fff;border:1px solid var(--line);padding:28px;margin:22px 0}.panel h2{font-size:25px;margin:0 0 20px}.form-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:18px}.field{display:flex;flex-direction:column;gap:6px;margin:12px 0}.field label{font-weight:700;font-size:14px}.field input,.field select,.field textarea{width:100%;border:1px solid #aebfbb;border-radius:2px;padding:10px 12px;background:#fff;color:var(--ink)}.field textarea{min-height:115px}.field.full{grid-column:1/-1}.helper{color:var(--muted);font-size:13px}.table-scroll{overflow-x:auto}table{border-collapse:collapse;width:100%;font-size:14px}th,td{text-align:left;border-bottom:1px solid var(--line);padding:12px 10px;vertical-align:top}th{color:var(--muted);font-size:12px;text-transform:uppercase;letter-spacing:.08em}td a{font-weight:700}.pill{display:inline-block;background:var(--mint);border-radius:50px;padding:2px 9px;font-size:12px;font-weight:700;color:var(--teal)}.danger{color:#a34535}.login-panel{max-width:480px;margin:70px auto 110px}.muted{color:var(--muted)}.question{border-top:1px solid var(--line);padding:17px 0}.question strong{display:block;margin-bottom:9px}.radio-option{display:block;margin:5px 0}.radio-option input{margin-right:9px}.inline-form{display:inline}.sr-only{position:absolute;left:-10000px;width:1px;height:1px;overflow:hidden}
@media(max-width:800px){.nav-wrap{align-items:flex-start;flex-direction:column;padding:20px 0}.site-header nav{gap:14px}.hero-grid,.intro-grid,.card-grid,.footer-grid{grid-template-columns:minmax(0,1fr)}.hero-grid>div{min-width:0}.hero-grid{padding-top:70px;min-height:0}.hero-art{height:300px;width:min(100%,400px);margin:auto}.stat-grid{gap:15px}.stat-grid strong{font-size:34px}.section-spaced,.intro-section{padding-top:60px;padding-bottom:65px}.people-grid{grid-template-columns:1fr}.form-grid{grid-template-columns:1fr}.portal-head{display:block}}
@media(max-width:520px){.container{width:min(100% - 32px,1160px)}.site-header nav a{font-size:13px}.hero h1{font-size:clamp(34px,9vw,42px);overflow-wrap:break-word}.hero .actions{gap:14px}.hero-art{height:250px}.stat-grid{grid-template-columns:1fr}.stat-grid div{border-right:0;border-bottom:1px solid #587076;padding-bottom:17px}.stat-grid div:last-child{border:0}.page-hero{padding:50px 0}.lead{font-size:18px}}

/* Accessibility controls and user-selected modes */
.accessibility-link{display:inline-flex;align-items:center;gap:5px;color:var(--teal)!important}.a11y-options{border-top:1px solid var(--line);margin-bottom:28px}.a11y-option{display:grid;grid-template-columns:1fr auto;align-items:center;gap:24px;padding:25px 0;border-bottom:1px solid var(--line)}.a11y-option h2{font-size:23px;margin:0 0 6px}.a11y-option p{color:var(--muted);margin:0}.a11y-toggle{min-width:105px;text-align:center;border:2px solid var(--teal);border-radius:3px;padding:9px 14px;font-weight:800;text-decoration:none}.a11y-toggle[aria-checked=true]{background:var(--teal);color:#fff}
:focus-visible{outline:4px solid #f0b429;outline-offset:4px;border-radius:2px}.skip:focus{left:12px;top:12px;z-index:1000;color:#000;background:#fff;border:3px solid #000;text-decoration:underline}
.a11y-large{font-size:120%}.a11y-large .container{width:min(1180px,calc(100% - 56px))}.a11y-large p,.a11y-large li{line-height:1.8}.a11y-large .site-header nav a{font-size:16px}
.a11y-links a:not(.button):not(.theme-dot):not(.brand){text-decoration:underline!important;text-decoration-thickness:2px!important;text-underline-offset:3px}
.a11y-contrast{--ink:#fff;--muted:#fff;--teal:#ffdf00;--mint:#222;--paper:#000;--line:#fff;--accent:#ffdf00;--hero-a:#000;--hero-b:#000;--hero-c:#000;--footer:#000;--art-1:#ffdf00;--art-2:#333;--art-3:#111;--orbit:#fff;color:#fff;background:#000}.a11y-contrast .site-header,.a11y-contrast .card,.a11y-contrast .person,.a11y-contrast .panel,.a11y-contrast input,.a11y-contrast select,.a11y-contrast textarea{background:#000;color:#fff}.a11y-contrast .site-header nav a,.a11y-contrast .brand,.a11y-contrast a{color:#ffdf00}.a11y-contrast .button,.a11y-contrast .a11y-toggle[aria-checked=true]{background:#ffdf00;color:#000}.a11y-contrast .hero-art{background:#000;border:2px solid #fff}.a11y-contrast .medical-tags span{background:#000;border:2px solid #ffdf00;color:#ffdf00}.a11y-contrast .footer p{color:#fff}.a11y-contrast .theme-dot{border-color:#fff!important}
.a11y-motion{scroll-behavior:auto}.a11y-motion *,.a11y-motion *::before,.a11y-motion *::after{scroll-behavior:auto!important;animation:none!important;transition:none!important}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*,*::before,*::after{animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important}}
@media(max-width:800px){.accessibility-link span{display:none}.a11y-option{grid-template-columns:1fr}.a11y-toggle{justify-self:start}}
.brand small em{display:block;margin-top:4px;font-style:normal;font-size:8px;letter-spacing:.14em;color:var(--muted)}
.brand-lockup{display:flex;align-items:center;gap:13px;flex:0 0 auto}.mef-mark{display:flex;align-items:center;justify-content:center;width:54px;height:58px;padding:7px;background:var(--ink);border-radius:2px}.mef-mark img{display:block;width:42px;height:43px;object-fit:contain}.mef-mark:hover{filter:brightness(1.15)}.a11y-contrast .mef-mark{background:#000;border:2px solid #fff}
.hero-photo{margin:0;overflow:hidden;border-radius:3px;background:#fff;box-shadow:18px 18px 0 color-mix(in srgb,var(--teal) 18%,transparent)}.hero-photo img{display:block;width:100%;height:100%;object-fit:cover}.hero-photo figcaption{position:absolute;left:18px;bottom:18px;background:color-mix(in srgb,var(--ink) 90%,transparent);color:#fff;padding:8px 12px;font-size:13px;font-weight:700;letter-spacing:.02em}.a11y-contrast .hero-photo{border:2px solid #fff;box-shadow:12px 12px 0 #ffdf00}.a11y-contrast .hero-photo figcaption{background:#000;color:#fff;border:1px solid #fff}
.method-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:14px;margin:28px 0}.method-card{background:#fff;border:1px solid var(--line);padding:24px}.method-card>span{display:flex;align-items:center;justify-content:center;width:38px;height:38px;border-radius:50%;background:var(--mint);color:var(--teal);font-weight:800}.method-card h3{font-size:21px;margin:18px 0 9px}.method-card p{font-size:16px;margin:0}.method-figures{display:grid;grid-template-columns:1fr 1fr;gap:14px;margin:20px 0 45px}.method-figures figure{margin:0;background:#fff;border:1px solid var(--line)}.method-figures img{display:block;width:100%;height:245px;object-fit:cover}.method-figures figcaption{padding:11px 14px;color:var(--muted);font-size:14px}
.method-card h2{font-size:21px;margin:18px 0 9px}.equipment-gallery{display:grid;grid-template-columns:1fr 1fr;gap:14px;margin:24px 0;align-items:start}.equipment-gallery figure{margin:0;background:#fff;border:1px solid var(--line)}.equipment-gallery .equipment-wide{grid-column:1/-1}.equipment-gallery img{display:block;width:100%;height:auto}.equipment-gallery figcaption{padding:12px 15px;color:var(--muted);font-size:14px}
@media(max-width:650px){.method-grid,.method-figures,.equipment-gallery{grid-template-columns:1fr}.method-figures img,.equipment-gallery img,.equipment-gallery .equipment-wide img{height:auto}.equipment-gallery .equipment-wide{grid-column:auto}}
@media(max-width:520px){.mef-mark{width:46px;height:50px}.mef-mark img{width:36px;height:37px}.brand-lockup{gap:10px}}