NPOO / MEDICAL RESEARCH · NEUROLOGY

How does the nervous system respond to everyday challenges?

A clinical study of the autonomic nervous system in people with multiple sclerosis and myasthenia gravis.

✚ Clinical neurologyANSMSMG
Functional autonomic nervous system testing room at the Department of Neurology, University Hospital Centre Zagreb
Autonomic testing laboratory

Autonomic reserve reflects the capacity to adapt.

The autonomic nervous system helps the body maintain balance during standing, thinking and other demands. This project examines whether those responses differ in people with multiple sclerosis or myasthenia gravis compared with healthy participants.

Aims and methods →
48planned months
200planned participants
3study groups

From clinical responses to molecular findings

01

Clinical assessment

Autonomic symptoms, fatigue, mood and quality of life.

02

Functional testing

Autonomic responses to orthostatic and cognitive challenges.

03

Data integration

Comparison of functional measures with selected molecular markers.